30/11/10: SureSelect XT webpage updated
November 30, 2010 by Peter · Leave a Comment
Agilent’s genomics website has been updated to give more details about SureSelect XT which are specially packaged kits which cover the whole NGS workflow process from gDNA extraction, library preparation, target capturing and sample and library QC and quantification. They provide an “end-to-end” solution for NGS-enrichment. Furthermore, these kits are designed to fit with automation of these processes.
Visit the SureSelect XT webpage.
29/11/10: Nine Good Reasons for Ordering EnPresso Today
November 29, 2010 by Peter · Leave a Comment
Here is the text of an email sent out by BioSilta today. EnPresso is a great product if you are looking to increase your protein production in small volume, shaken cultures. It will help you if you are a researcher involved in protein (enzyme) screening and protein structural studies (e.g. protein crystallography).
24/11/10: Special Price when You purchase Bioanalyzer and MX qPCR Instrument Together!
November 24, 2010 by Peter · Leave a Comment
If you are working in the field of molecular biology / genomics, Agilent’s 2100 Bioanalyzer and Mx3005P QPCR Systems are a great combination to enhance the quality of your research.
Both instruments can become an integral part of your work, producing reproducible and reliable data. Take a look at these exciting features:
2100 Bioanalyzer
- Ready to use assays and reagent kits for RNA, DNA and proteins
- Save your precious sample – use just 1-4 µl
- Digital data for convenient analysis, data sharing and archiving
Mx3005 qPCR
- Advanced scanning optical design gives large dynamic range of detection and reproducible results
- Five interchangeable filter options gives ultimate flexibility for the assays you use
- The most user-friendly qPCR software available – MxPro.
Contact You Do Bio to find out about exciting discounts when purchasing a 2100 Bioanalyzer and an Mx3005P.
24/11/10: Agilent Introduces GeneSpring GX 11.5
November 24, 2010 by Peter · Leave a Comment
Agilent has released GeneSpring GX 11.5, an expansion of its popular bioinformatics software into visualizing and analyzing multiple types of biological data. GeneSpring GX 11.5 now interprets exon microarray, proteomics and metabolomics experiments together for the first time, using a familiar interface.
These new capabilities join existing GeneSpring GX applications for gene expression analysis, genomic copy analysis, genome-wide association analysis and transcriptomics data analysis.
Read a full press release describing the new version of GeneSpring here.
22/11/10: Agilent Release All Exon Arrays
November 22, 2010 by Peter · Leave a Comment
A cut and paste from the Agilent website. I think this is an interesting product:
Agilent Technologies Inc. (NYSE: A) today announced a solution for exon analysis based on SurePrint G3 Exon Microarrays. The solution provides a major expansion of Agilent’s portfolio of gene expression reagents, microarrays and bioinformatics systems. This new system, available in mid-November, enables researchers to examine alternately expressed exons according to recently updated content, providing a global picture of RNA expression.
“We’re continuing to fill out our gene-expression workflow with high-performance, cost-effective tools from RNA isolation kits through data interpretation and validation,” said Sharoni Jacobs, Ph.D., Agilent product manager, Gene Expression. “In December we introduced the Low Input Quick Amp labeling kit, which requires only 10 nanograms of total RNA. Last May, we launched the third-generation SurePrint G3 Gene Expression microarrays, which include both coding and non-coding RNA targets on a single array.”
Agilent is leveraging the performance and density of the SurePrint platform to provide a full-exon solution to help researchers discover the relationships between approximately 30,000 genes and more than 100,000 proteins.
Agilent SurePrint G3 Exon Microarrays enable researchers to identify both gene-level and exon-level expression changes in a single experiment to capture subtle but important biological changes. RNA is prepared for hybridization using Agilent’s Low Input Quick Amp WT labeling kit for whole transcript labeling. Agilent’s GeneSpring GX 11.5 bioinformatics system increases productivity even more by helping investigators analyze gene-level data and splicing indexes simultaneously.
“Exon level arrays represent a significant step up in our ability to interrogate the genome in greater detail than traditional 3 prime biased arrays,” said early access user Stuart Pepper, head of the Cancer Research U.K. Molecular Biology Core Facility at the Paterson Institute for Cancer Research, The University of Manchester. “Our initial work with these arrays has shown that we can obtain very clean data which will facilitate the detection and quantitation of alternate transcript expression.”
Agilent offers catalog content for human, mouse and rat in 4x180K (four arrays per slide, 180,000 features each) and 2x400K formats, letting users choose between cost, throughput and comprehensive coverage. Like its other microarrays, Agilent also provides custom options for the human, mouse and rat SurePrint G3 Exon products. Custom formats include 8x60K, 4x180K, 2x400K and 1x1M.
Like all Agilent microarrays, the SurePrint G3 Exon solution delivers a wide dynamic range to detect low expressors and high expressors to accurately represent the range of expression levels and provide high confidence in the results.
Agilent provides the industry’s widest selection of gene expression solutions, offering a comprehensive portfolio with the highest array sensitivity, a proven and reliable qPCR platform, and an integrated software solution that streamlines the workflow, all with a focus on quality results.
12/11/10: Announcing the Agilent Genomics eSeminar Series
November 12, 2010 by Peter · Leave a Comment
Agilent have started an eSeminar series (kept it kind of quiet, if you ask me) that covers some very interesting subjects. Upcoming events include eSeminars on SureSelect, exon arrays, gene expression, methylation. Seminars can be viewed live, or downloaded later.
The main eSeminar page is here.
12/11/10: Latest Agilent Genomics Newsletter
November 12, 2010 by Peter · Leave a Comment
The latest Agilent genomics newsletter can be accessed online here.
Highlights include:
- New products for Target Enrichment System
- CGH + SNP arrays
- Exon microarrays
08/11/10: Automation of NGS Library Prep and more
November 8, 2010 by Peter · Leave a Comment
Agilent have worked extremely hard to put together an automated solution for the preparation of next generation sequencing libraries. The system is based around the flexible components in Agilent Automation Solutions and allows preparation of libraries for Illumina, SOLiD and 454 systems. 
By starting from the basic Bravo system, users can build up to a true walkaway solution. In addition, the system can still be used for other laboratory procedures, e.g. qPCR set-up, dilutions, replications, sample purifications, sample labelling – you name it.
Please take a look at this new data sheet (PDF file) from Agilent about the SureSelect XT System, for library preparation and SureSelect target enrichment.
08/11/10: Agilent Launch Genomics Workbench 6.5
November 8, 2010 by Peter · Leave a Comment
Agilent have announced the release of Agilent Genomic Workbench 6.5, which includes analysis capabilities supporting the new SurePrint G3 CGH+SNP Arrays. This feature allows the CGH+SNP arrays to be used for simultaneous detection of copy number changes and copy neutral LOH/UPD in the same workflow.
Click here to learn more and get a download for a trial period. Get an overview of AGW 6.5 in this document (PDF File): AGW 6.5 Datasheet
Exciting new features in the AGW 6.5 release:
- Ability to analyze Agilent CGH+SNP microarray data to identify and visualize copy number and copy-neutral LOH calls side-by-side.
- Easy installation and on demand data download allows users to install fully functional AGW6.5 in less than 30 minutes.
- Agilent Literature search CytoScape plug-in allows user to design custom microarrays around biological context of interest through eArrayXD.
- Entire Agilent SNP data set is available for download and search for designing custom CGH+SNP microarray in eArrayXD.
- Genotypes of 5 HapMap reference samples are pre-loaded for usage in DNAAnalytics.
- More efficient QC reporting of Target Enrichment data in workflow mode.
