17/03/16: Spring Offers on Microplate Readers and Washers

  For a limited time only, Molecular Devices are offering up to 50% off* certified pre-owned and ex-demo SpectraMax® Multi-Mode Microplate Readers and UV-visible absorbance and ELISA Single-Mode Microplate Readers and Microplate Washers, whilst stocks last. But hurry because this offer ends on March 30, 2016! You could benefit from: Up to 8 different detection modes The latest…

11/09/15: SpectraMax i3x – the multi-mode microplate reader that evolves with your future needs

When is a microplate reader not just a microplate reader? When it is the SpectraMax i3x from Molecular Devices. Yes, it can read microplates. But did you know that it can be instantly upgraded to new measurement capabilities, can scan Western Blots and imaging cytometry? Check out the video below: [youtube]https://www.youtube.com/watch?v=4oA0QSZhRC4[/youtube] Contact You Do Bio…

03/09/15: Development of a Cav1.3 channel assay using optogenetic methods

Cav1.3 is an L-type voltage-gated calcium channel and an important therapeutic target for drug discovery. There is a growing demand for the development of high-throughput assays to evaluate channel blockers under different states, as this likely provides highly-desired selectivity for pathologically over-activated Cav1.3 channels. However, current screening methodologies for this channel have significant limitations. Molecular…

14/08/15: Antibody Discovery Solutions from Target Validations to Scale Up

Find out how you can optimize productivity with a complete solution of instruments and reagents that address all stages of antibody discovery research – with this eBook from Molecular Devices (pictured right). Topic highlights: Measuring protein marker expression Homogeneous antibody binding and intracellular localization assays High-throughput development and selection of hybridomas and GPCR cell lines Rapid and…

13/08/15: Identifying Early Lead Targets Against GPCR and Ion Channel

Download Molecular Devices eBook to learn about novel applications and solutions for identifying early leads against GPCRs and ion channel targets. Includes links to application notes, posters and webinars on: Comparison of intracellular calcium measurements Potassium ion channel assay for high-throughput screening Characterization of hERG channel blockers High-throughput cardiotoxicity assays using stem cell-derived cardiomyocytes If you…

12/08/15: Characterizing the Viability and Morphology of 3D Cancer Spheroid Cultures

Are you interested in cancer cell lines that will form spheroids on a 3D matrix? Such cell lines present the possibility to bridge the gap between in vivo and in vitro translational research. Molecular Devices have made available Dr. Oksana Sirenko’s recent poster on enabling rapid imaging and analysis of 3D spheroids in microplates. From this you will learn more about…

12/05/15: Wells to Westerns: Investigating the Cellular Heat Shock Response

A free app note from Molecular Devices. Investigating a cellular response can involve multiple approaches to gathering information—imaging, cell-based viability and proliferation assays, Western blots to look at changes in protein expression and more. Often multiple instrument platforms are needed to glean the necessary results and several software packages may need to be learnt in the…